A study showed that engaged women want to lose on average 20 pounds to look great on the big day. A doc in Florida is offering the Ketogenic Enteral Diet (K-E diet) for ladies wishing to slim down before their nuptials. The diet lasts 10 days, costs $1.5K, and causes approximately a 10lb weight loss. The ketosis is monitored using ketostix which are widely available for diabetics. The dieting ladies are permitted nothing caloric by mouth. Great idea? Not so fast. It's not that hard to eat a calorie-restricted ketogenic diet without paying $1.5K and having a tube up your nose. Think about it.

SOURCE
http://www.nytimes.com/2012/04/15/fashion/weddings/Losing-Weight-in-Time-for-the-Wedding.html?_r=1&pagewanted=all
http://www.medpagetoday.com/CelebrityDiagnosis/32229

http://www.medscape.com/viewarticle/745359?src=mp&spon=34
is a review on this study:

Wilson KM, Kasperzyk JL, Rider JR, et al. Coffee consumption and prostate cancer risk and progression in the health professionals follow-up study. J Natl Cancer Inst. 2011;103:876-884. Epub 2011 May 17.

but this study
http://cancerres.aacrjournals.org/content/50/21/6836.short
found no correlation at least for survival of fatal prostate cancer, between coffee drinkers or not.

( ...and... coffee drinkers have higher testosterone! text here. video at link above.Collapse )

What the first step in making bile?
7 alpha hydroxylation of cholesterol
this is the rate limiting step, inhibited by presence of bile acids
cyp enzyme requires iron 2+ and NADPH, and forms water

What happen to iron in the reaction?
Fe2+-->3+
( notesCollapse )