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Entries by tag: fibromyalgia

 Noon talk in room 301 at NUNM
"Biofilms == What has the last 200-Million Dollars in Research Taught Us"
copyrighted powerpoint--PS anderson
www.consultDrA.com

his presentation:
evaluation of biofilm research
clinical relevance

10 yrs ago involved in cancer research at Bastyr, 5 yr NIH trial
next research--undiagnosable nonhealing illnesses
junk drawer dxs: fibromyalgia, rheumatologic conditions not well differentiated
what were impediments to cure?
nutrigenomics
multiple causes, multiple organ systems involved, often dxd as rheumatologic condition
most had lab verifiable infections, not cleared by usual treatments

research review 20 years later
NIH and CDC have ID'd biofilms as highest threat to human health
but haven't publicized it because they don't know what to do about it

clinically trying things, some worked, some didn't
doing OK
a few years forward--at oncology think tank meeting
met a guy doing biofilm research, 12 million dollars funding, 11 million in Anderson's Q's
last million will be FDA approved interventions for biofilms
government "disappears" some of the research
he got more sources from this guy, looked at the research, is sharing sources with us in his powerpoint

biofilm becomes a resistance factor for the microbe
resistant to antibiotics

lives "anyplace wet": blood vessels, mouth, (me: what about gut, lungs/bronchi, sinuses?)
biofilms start in the gut and get more severe, cause significant immune response when disrupted
sick long enough: more microbes migrate there
it gets bigger, from thin to thick, from low diversity to high
the worst biofilms are "phase 2" become their own microbe
can contain bacteria, parasites, viruses, fungi--they share DNA
treatments don't work: kill one but the rest survive
cure one thing and another thing pops up

clinically relevant in sicker population, chronically ill
lots of suppressive treatments, incomplete treatment
many microbes involved
pseudomonas and gram negatives
mycoplasma
H. pylori (symptomatic)

treatments for phase 1 are enzymes and such
work pretty well
patients usually not that sick

Biofilm summary from Stephen E. Fry MD (in power point)
Biofilms are considered the rule in nature rather than the exceptoin.  If you have chronic infection, biofilms may be an underlying cause.  Many, if not most, ....

testing for biofilms
can't really?

prevention - phase 1 agents
goals: inhibit quorum sensing, initial attachment, organism efflux pump
MORE ON THIS SLIDE
enzymes
aromatics--oregano, garlic, olive, etc (daily consumption of these = best prevention)
tannins
phenolics
xylitol, stevia
nigella = black cumin--can be used for phase 2 as well, plant immune modulators, wedges into biofilms

phase 2 later biofilm
not treatable with phase 1 agents except black cumin
synthetic antimicrobials
direct biofilm disruption--agents - ?? PO, IV
product: biocidin, he likes it, goes to phase 1.5 ish

oral bismuth (ionic)
EDTA, calcium-disodium EDTA and Na2-EDTA as additive to immune and abx IV formulas for pts who may have biofilm
silver nanoparticles, low 23 PPM nasal spray or 200-500ppm for other systems, hydrosol not colloidal
anti-infective: H2o2, HDIVC, Ge, Zn, etc

BEG bactroban, e and gentamycin

thiols (mono-) ALA (Oral or IV), NAC (oral or IV, or nebulized for resp), glutathione (IV or nebulized)
(ala and nac will cause strange gut reactions when added, this indicates that there's a biofilm)
thiols (di-) DMSA (oral, 300-500mg po away from food bid day prior to and of the IV anti-infective), DMPS (IV and oral)

oral bismuth-thiol complex--neither alone, a new molecule (do not use IV bismuth at this time, heavy metal)
combo: the last million he hadn't figured out yet
little to no chelation effect.  dithiol is bound to bismuth so toxicity of bismuth and chelating ability are "negated"
bismuth nontoxic in this form, new mol will show up on heavy metal testing as bismuth
wedges into the biofilm and reacquaints the immune system with what's in there: the "wedge effect"

HIS FORMULA:
DMPS 25mg, ALA 100mg, bismuth subnitrate 200mg per cap
ideally no substitutions
DMSA 100mg can sub for DMPS
bismuth subcitrate can sub for subnitrate (weaker product)
this is the strongest formula that can be made, stronger products have been sequestered by the govt

take for 60 days---more on slide

other supports needed for about a month
many need adrenal support
if on low dose hydrocrotisone and adrenal support they will probably need 2-4x more hydrocorisone
if on non-rx adrenal support they may need 5-10x the dose for "a time"
some need thyroid support

his otc version
Bis-thiol plus buck cumin

support immune system during tx
support healthy microbiome

when biofilm opens up you get an immune response
achy, headache, fever, possible psych sx
can be big crisis if you are not ready for it
very acute
must warn patient ahead of time--if they start feeling terrible that's a good sign
return of early sx is likely: sign of treatment success
if healing crisis does not subside: bugs dying releasing metallotoxins or broad spectrum herbals aren't heavy duty enough
duration of treatment relates to duration of illness, up to 2 years

immune suppressed patient
won't get fever, cytokine storm
treat presumptively, prescription anti-infectives to hedge bets

this article has all the same references as this talk
http://ndnr.com/gastrointestinal/biofilms-what-have-we-learned-from-the-research/
and webinar on priority one

fasting?
get stronger/faster reaction with it






BALNEOTHERAPY MUD AND CLIMATOTHERAPY AT THE DEAD SEA
lecture by Shaul Sukenik - Soroka University Medical Center and
Faculty of Health Sciences,
Ben Gurion University of the Negev
Beer-Sheva, Israel
notes from recording of this presentation which was given in October 2008Collapse )

PAIN and Neuropathy

Pain =
--a feeling of distress, suffering, or agony,
--an unpleasant sensation that can range from mild, localized discomfort to agony
--has physical and emotional components
--emotions have strong effects on physical perception
--algophobia = an irrational dread of pain
--depression etc strongly associated with inadequately treated pain
--also "pain" = painful uterine contraction occurring in childbirth.
--from the Latin "poena" meaning a fine, a penalty
--acute or nociceptive pain vs neuropathic pain
--nociceptive and neuropathic pain are caused by different neuro–physiological processes, and therefore tend to respond to different treatment modalities
moreCollapse )

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