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Entries by tag: alzheimers

The National Institutes of Health, 10 large drug companies and seven nonprofit organizations announced an unconventional partnership on Tuesday intended to speed up development of drugs to treat Alzheimer’s disease, Type 2 diabetes, rheumatoid arthritis and lupus.

During the course of a five-year, $230 million effort, the participants will share data in regular conference calls and meetings, working together to determine which findings are likely to lead to effective treatments. They will make their findings and data publicly available.


...What concerns me about this is the emphasis on drugs. There are better ways to adjust physiology than taking in foreign substances. And there are more useful things we could study. Like food, and exercise, and how to they affect our biochemical and electrical mileau. Sex, we should throw more money at studying sex and how it affects neurotransmitters. On the effects of chewing gum and on understanding the endocrinology of sexual preference. And on why our hearts slow down as we age, and a million other questions. I'm just curious: I really want to know the answers. I wish that the money spent on medical research was directed more by altruism and less by profit motive.

SOURCE
http://www.nytimes.com/2014/02/05/health/nih-joins-drug-makers-and-nonprofits-on-stubborn-diseases.html
A new study shows that patients with mild cognitive impairment (MCI) do not progress to dementia if they drink enough coffee! Gotta love it. I'm going to start drinking a whole pot, by golly. The researchers in this study think that it's the caffeine, and not the anti-oxidants, that has the anti-dementia effect, but according to mouse studies, it has to be coffee. Those patients with a little MCI who java it up enough to have a plasma caffeine level of 1200ng/mL did not go into dementia. 100%. The caffeine appears to inhibit an enzyme used in the manufacture of beta amyloid! They're also tracking cytokines in the plasma and finding that there's a particular profile assorted with conversion to Alzheimer's disease (low IL-6, IL-10, and G-CSF). In the future we might consider testing for those cytokines to detect impending dementia in healthy patients.
notes!!Collapse )

Aging Brains can Flatten your Finances

http://www.telegram.com/article/20110710/NEWS/107109970/1237

Makes the case that as we age, we should get our ducks in a row for the possibility that we ourselves might not make the best decisions about money in our old age.
http://www.jarrow.com/product/188/Neuro_Optimizer consider this product via Vitacost



MY QUESTIONS
what are food sources of citicholine? can we get it from eating brains?
there is choline in eggs and liver. is there citicholine?? how much??
how easily does choline convert to citicholine?
can we support the conversion?
can we by pass this supp using diet???

CHOLINE DEFICIENCY is common (not citicholine, mind you!)
suspect if: fatty liver, hemorrhagic kidney necrosis, infertility, growth impairment, bone abnormalities, hypertension, cancer, atherosclerosis, glaucoma, neuro dz: Alzheimer's,. bipolar. LABS: incr ALT, incr HCYS

notes, some background, linksCollapse )

The Healthiest Diet

Which diet is the healthiest, according to the science, as reported by Dr Schor?
the Mediterranean dietCollapse )
(Reuters) - People with insulin resistance and type 2 diabetes are more likely to develop plaques in the brain associated with Alzheimer's disease, researchers in Japan reported on Thursday.

The study involved 135 elderly participants in the town of Hisayama, Fukuoka prefecture, who had their blood sugar levels checked several times at the start of the study. They were then monitored for signs of Alzheimer's disease for 10 to 15 years.

After they died, researchers conducted autopsies on their brains and found plaques, particularly in those who had high blood sugar levels while they were alive.
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