liveonearth (liveonearth) wrote,
liveonearth
liveonearth

Acromegaly

What are the face, skull and foot changes seen with acromegaly?


ACROMEGALY
--dt pituitary eosinophilic adenoma secreting growth hormone AFTER growth plates have fused

--excessive growth hormone production PRIOR to closure of long bone growth ctrs-->gigantism:


-->back to acromegaly

--facial changes: prominent forehead, thickened tongue

--hands: broad and large, widened shafts, bony protuberances, enlarged distal tufts (spade like), widened joint spaces (dt cartilage overgrowth)


--predisposition to degenerative arthritis, esp of spine and weight bearing jts
--predisposition to carpal tunnel syndrome dt extra bone @ tendon attachments
--feet: heel pds greater than 20mm thick dt soft tissue and spurs

--spine: increased size, hyperostoses, widened disc heights, posterior body scalloping
--skull: sella turcica enlargement (dt pituitary neoplasm), sinus overgrowth (esp frontal), malocclusion, widened mandibular angle (prognathism, jaw goes down not forward)
--prognathism:

--sella turcica and frontal sinus here:


Treatment flowchart:
Tags: bones, diagnosis, disability, hormones, imaging, nd2
Subscribe
  • Post a new comment

    Error

    Comments allowed for friends only

    Anonymous comments are disabled in this journal

    default userpic

    Your reply will be screened

    Your IP address will be recorded 

  • 7 comments