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Hyperparathyroidism


--three forms: primary (tumor), secondary (renal dz), and tertiary (renal dialysis)
--F>M, 3:1
--30-50 years of age
--S/Sx: weakness, lethargy, polydipsia, polyuria, elevated alk phos and parathormone levels
--X-ray: osteopenia, accentuated trabeculae, subperiosteal resorption (in hand, hallmark feature)
--HANDS: subperiosteal resorption, radial margins of proximal and middle phalanges of 2nd and 3rd digits show acroosteolysis (scooping)

--"tuft" resorption of fingertips, DDX: SLE, PVC exposure, scleroderma
--brown tumors (hemorrhagic giant cell proliferations, usu in finger, femoral head, tibia, rib)

--more bone changes: SI mb resorbed, distal clavicles, pubis, lamina dura around teeth, "salt and pepper" skull
--spine osteopenic, trabeculae accentuated, end plates concave, "rugger jersey" spine, bold horizontal stripes

--Soft tissue changes include: nephrocalcinosis, renal calculi, chondrocalinosis, calcification in various periarticular tissues and visceral organs, this is nephrocalcinosis:

Comments

( 2 comments — Leave a comment )
hausfrauatu
Mar. 16th, 2009 12:41 am (UTC)
That looks like a terrible thing to have!

I think I figured out what my issue is. I was having seemingly random flushing and tingling of my face. I have now observed that it's related to eating sugary or high GI foods. I have a family history of Type II. So it's a warning shot to lose some weight NOW. I'm guessing that the same thing is happening to the rest of my circulatory system as well. My blood sugar hasn't been stable since puberty, but has tended to be low. Ah...middle age...
liveonearth
Mar. 16th, 2009 02:41 am (UTC)
Wow you have a lot of different hereditary susceptibilities! Hope you don't have trouble from any of that stuff. Still, it probably would be a very good thing to get regular exercise. There is no faster way to reduce insulin resistance than to ramp up the physical plant.

I don't know about the flushing and tingling....those aren't usually the first signs of diabetes. Do you consume low calorie sweeteners? Some of those cause tingling. Better keep an eye on yourself!
( 2 comments — Leave a comment )

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