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Fructose


--US public consumes a lot
--3 main sources: sucrose (common table sugar), high-fructose corn syrup (HFCS) and fruit
--in fruit, fructose signals sweetness and good nutrition: our ancestors detected that flavor as goodness
--fructose intake was much smaller pre-sugar and HFCS
--fructose intake has been increasing for a long time but good data is hard to find
--Health and Nutrition Examination Survey (1988-1994): mean daily consumption was 54.7 g/d (range: 38.4-72.8 g/d) and was 10.2% of total daily caloric intake. Consumption was highest among adolescents (12-18)(72.8 g/d, or 12% of total calories, 1/4 of these got 15%+ of calories from fructose, largest sources was sweetened drinks 30%, grains 22%, fruit/fruit juice 19%)
--sugar beverages (soda pop) have no nutritional value other than calories
--50% of sugar is fructose and 55% of HFCS is fructose
--calories in calorically sweetened beverages are not perceived by the body in the same way as those in solid food -->"add-on" calories to the other foods in the diet rather than suppressing intake of other foods
--obesity epidemic could be explained by the consumption of an extra 20-ounce soft drink each day
--sugar = "pure, white and deadly," --Professor Yudkin in 1986
--Yudkin said 25 years ago "I suppose it is natural for the vast and powerful sugar interests to seek to protect themselves, since in the wealthier countries sugar makes a greater contribution to our diets, measured in calories, than does meat or bread or any other single commodity."
--Swiss study: dietary fructose predicts increased low-density lipoprotein cholesterol in children
--fructose (unlike other sugars) increases serum uric acid levels perhaps due to liver metabolism of fructose
--ATP used by phosphofructokinase to phosphorylate fructose-->fructose-1-phosphate
--ADP formed-->AMP-->inosine 5'-phosphate-->uric acid
--high levels of uric acid may -->cardiovascular disease by reducing the availability of nitric oxide
--NO maintains normal BP and blood vessel wall fx
--nature preferred glucose over fructose as a substrate for metabolism during the evolutionary process
--soft drink consumption linked to development of cardiometabolic risk factors and the metabolic syndrome (Framingham Study)
--individuals consuming at least 1 soft drink/d had more metabolic syndrome
--fructose intake is directly related to risk for gout in men.
--public schools are selling this junk to kids!!!!

SOURCE:
http://www.medscape.com/viewarticle/575891?src=mp&spon=34&uac=89474MT
From The Medscape Journal of Medicine
Clinical Nutrition and Obesity - Editorial
Fructose -- How Worried Should We Be?
Posted 07/09/2008
George A. Bray, MD

Comments

( 3 comments — Leave a comment )
rinku
Jul. 21st, 2008 07:29 pm (UTC)
Fructose works differently in the body from HFCS -- too much fructose is bad of course, but they do work differently enough that I think it's misleading to call HFCS fructose.
liveonearth
Jul. 22nd, 2008 01:17 am (UTC)
HFCS has a lot of fructose in it, they are clearly not the same thing and I'm sorry if my notes make it sound that way. Fructose is processed in the liver instead of being taken in directly by all cells like glucose.
liveonearth
Jul. 22nd, 2008 01:18 am (UTC)
HFCS has a lot of fructose in it, they are clearly not the same thing and I'm sorry if my notes make it sound that way. Fructose is processed in the liver instead of being taken in directly by (nearly) all cells like glucose.
( 3 comments — Leave a comment )

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