Just ran across a nice southern article about eating the leaves as salad, and painting the skin with the toxic berry juice. I have been taught to use an alcohol extract of the root as a "lymphogogue" meaning it is supposed to stimulate lymph movement, or at least a strong immune response. Far as I know there is no science to support this use. The juices of the root are very strong and caustic, and it should not be handled with bare hands.