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Environmental Medicine (week 11): Treatment


detoxicate = remove toxic principle of a substance
detoxify = remove toxic quality
depuration = free from impurities
depurant = medicine that purifies through removal of excreta
(from Env Med Tx by Walter Crinnion ND 2004)

Assortment of articles by Crinnion posted on Moodle

FACTORS IN DEPURATION
age, gender, diet, lifestyle
environmental exposures
disease state
genetic polymorphisms
supplement use
intestinal health
mental state

3 STEPS
avoid exposure: make home safe, esp bedroom, need place for true healing, remove all sources from home
enhance elimination
mobilize stored toxics

RESOURCES
Eco-Healthy Homes (OEC resource)
www.oeconline.org/our-work/kidshealth/tinyfootprints/eco-healthy-homes-checkup-kit
can download kit for free, get copies to share, get presentation at your place
can give to anyone even impoverished

Healthy eHomes (WebMD)
http//www.webmed.com/heatlh-ehome-9/default.htm
web based tool, high end test

Healthier Homes (HHI)
www.healthhouseinstitute.com
high end

HOME CHECKLIST
HEPA air filter
HVAC (vents, furnace)
*pull rest of list from notes
construction materials
pipes, water supply
paints, solvents
cleaning supplies
carpeting, cushions
lawn chemicals
hygiene products
laundry
electrical devices
hobbies, toys
food

WORKPLACE
protective gear
carpet
copy machine
"fragrance free"
HEPA filter
check MSDS for toxic health effects
ask co-workers re sim sx

TX PRINCIPLES
assess: vitality, body burden, extent of dz process, available resources and potential
assist inherent healing process
depuration protocols vary drastically, always personalized, monitor and adjust tx
PARQ re: toxin release and healing crisis, exacerbations of past sx, long process
base tx regiment on sx not labs
always do HPI, exam and basic labs: chem, CBC, UA, consider extra: CDSA, EKG, etc
Tx whole person, maintain nutrition, hydrate, open emunctories

NUTRITION FOR DETOX
EFAS upreg CYP activity
high sat fat and low PUFA -->decr glutathione
low prot incr tox of heavy metals, pesticides via decr CYP and GSH, lack of phase 2 conjugation moieties
high carbs-->decr CYP fx and phase II

A CLEANSE
is a journey
therapeutic
transformative
cathartic
encourage "letting go" of many things
include mental-emotional cleanse, release and renewal

LUNGS
deep breathing exercises
regs parasymp response
alkalinizes blood
forces pt to slow down
10-15 mins 2-3x/day

VISUALIZATION
out with the bad in with the good
nature themes

HYDROTHERAPY
for everybody, daily
sauna, enema, colonic, shower, bath
high temp to 130F, range 120-180F (50-80C)
radiant vs far-infrared (better) no research on depurative effects
2 saunas/week min, 20 MINS MIN
*sauna-->decr BP and CVD risk in HTN pts
CI: high risk preg, CVD, malignant HTN, recent MI, unstable angina
aldosteronism, Conn's syndrome, Addison's dz, Cushing's dz
relative CI: decompensated heart failure, arrhythmia, stroke, TIA

REA PROTOCOL
EHC Dallas
sauna plus clean diet and environment
improves chemical sensitivity sx
informahealthcare.com/doi/abs/10.3109/13590....more

HEAVY METALS RELEASED IN SWEAT
antimony, cadmium, lead, mercury, nickel
pcbs, organophosphates, solvents, multiple pharamceuticals
also essential elements: bromide, chloride, chromium, Cu, Fe, K, Na, Mg, Mn, Zn

SUPPORT PHASE II FIRST
Phase I may create more toxic intermediates
parathoin-->paraoxon
ethanol-->acetylaldehyde

SUPPORTING PHASE I DETOX
Iron: heme production
Copper: superoxide dismutase
Magnesium: ATP and CYP production
Zinc: alcohol dehydrogenase, SOD
Manganese: SOD, GSH
Molybdenum: aldehyde oxidase to process formaldehyde, vinyl chloride, solvents
Vit A, C, E are antiox, vit C incr CYP fx
Thiamine B1 cofactor for enz
Riboflavin B2: flavin mono/di nucleotide (FMN, FAD), coenz for GSH, THFolate
Niacin B3: formation of NADPH

see notes to finish these lists
LIVER NOTES!!!

do not begin any depuration protocol until patient is eliminating regularly from intestine

CHOLERETICS TO BIND BILE
cholestyramine (phramceutical) questran sig 4-8g qd
olestra (food product) "fat free" sig 7-8 pototo chips qd per Dr Crinnion
proven to remove: PCBS, PFOA, Hexachlorobenzene
SE: abd cramping, N/D, lipophilic vit def

COLONICS prevents reabsorption of bile, stims lymphatic flow
nothing works better to empty the colon
ideal: 1-2x/week during
also enemas, coffee
fiber intake
charcoal, clay

WHEY
incr GSH

FINAL EXAM
posted on moodle on Friday

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