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SSRI's indicated for Schizophrenics!?

According to this short update on a new study that is. They tested 5 SSRI's on over 800 patients and found them "moderately" beneficial, with 3 of the SSRI's showing greater responses than the others. They want us to prescribe these antidepressants in addition to the antipsychotics that are standard 1st line therapies. My question: If the mechanisms of these 5 tested meds are the same, and presumably the doses are the same, why the difference in response among them? And how did placebo do? I'd like to know more about the stats--I don't just trust anybody's interpretation of stats these days. I certainly don't take for granted that anything medscape tells me is true, though I am interested in their conventional medicine perspective. Oh and I have more questions. What megacorp(s) made those 5 SSRI's? And what megacorp(s) paid for the research?

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( 2 comments — Leave a comment )
hausfrauatu
Apr. 19th, 2011 11:15 pm (UTC)
Huh. Go figure. That doesn't make a lot of sense, from what little I know about what little we know about what causes schizophrenia.
liveonearth
Apr. 19th, 2011 11:22 pm (UTC)
Depending on who did the science and how, and what meager support they need to claim a "moderate" benefit, these pills could have performed worse than placebo and we would never know about it. But it does also sorta makes sense that if somebody's schizo and their life is fubar, they might be depressed, and if they're depressed, more serotonin might cheer them up.....I think I will consider naturopathic support options for depression along with the tx for schizo in these cases...
( 2 comments — Leave a comment )

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